What is the most common benign salivary gland tumor in adults?

• A. Warthin tumor
• B. Mucoepidermoid carcinoma
• C. Pleomorphic adenoma (benign mixed tumor) of the parotid gland
• D. Adenoid cystic carcinoma

Answer: (C)

The most common benign salivary gland tumor in adults is pleomorphic adenoma, typically arising in the parotid gland. This tumor earns its title by its frequency: among salivary gland neoplasms, benign lesions predominate, and pleomorphic adenoma accounts for the largest share, especially in the parotid. It’s called a mixed tumor because its tissue shows a mix of epithelial elements and a mesenchyme-like (stromal) component, leading to a characteristic variably patterned, yet usually well-circumscribed, mass. Clinically it presents as a slow-growing, painless lump in the cheek region over years, which is a classic presentation in adults.

Warthin tumor is another benign parotid tumor but occurs less often than pleomorphic adenoma and is more linked to older age and smoking. The other two options represent malignant tumors, which, while important to recognize, are not the most common benign lesions.